High-res device gives retinal imaging a facelift

Rochester, NY-Retinal disease has been given a new face thanks to increased details of the adaptive optics scanning laser ophthalmoscope (AO-SLO), according to Mina Chung, MD.

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“AO-SLO imaging measures the wavefront aberrations and corrects them using a deformable mirror,” said Dr. Chung, associate professor of ophthalmology, Flaum Eye Institute, University of Rochester, NY. “The most recent designs allow for a 2-μm resolution that enables imaging of the cones at the foveal center, (and) rods can be resolved in the peripheral retina.”

With fluorescence AO-SLO, retinal pigment epithelium (RPE) fluorescence is used simultaneously to obtain images of the photoreceptors and the underlying RPE in the same retinal location.

Patients with retinal diseases can have poor fixation and ocular movements, which is challenging when attempting to obtain retinal images.

Investigators at the University of Rochester and Canon Inc. have developed a real-time, multi-scale stabilization system that uses a wide-field SLO with a tip/tilt mirror that compensates for gross movements, another closed-loop tip/tilt mirror in the AO-SLO to compensate for fine movements, and digital registration algorithms to remove the stabilized images, Dr. Chung said.

The multifocal IOL evolution

She described a patient with age-related macular degeneration (AMD) where the motion was corrected from 68 arc minutes to 0.08-arc minute, which allowed creation of an averaged image of the retina.

“These advances allow imaging in patients with poor fixation and poor vision,” she said.

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