Italian study illuminates positive outcomes and common complications of SING IMT implantation
The implant was tested in eyes of patients with bilateral age-related macular degeneration who underwent cataract surgery
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Investigators from the Department of Translational Medicine, University of Ferrara, and Sant’Anna University Hospital, both in Ferrara, Italy, conducted a study in which they evaluated the Smaller-Incision New Generation Implantable Miniature Telescope (SING IMT, Samsara Vision).
The authors reported that the device provided “promising objective results.” However, patients commonly reported unexplained blurred or hazy vision postoperatively that require further investigation,1 according to first author Ginevra Giovanna Adamo, MD.
This study evaluated the anatomic and functional outcomes of the SING IMT in patients with bilateral advanced age-related macular degeneration (AMD).
All patients in this non-comparative, retrospective, interventional case series included patients with bilateral late-stage AMD who underwent cataract surgery and implantation of the SING IMT at the Sant’Anna University Hospital. All procedures were performed by the same surgeon. The main outcomes were measurement of the corrected distance visual acuity (CDVA), near VA (CNVA) and the degree of endothelial cell loss (ECL). The investigators also recorded any complications that developed.
Results with the SING IMT
Adamo and colleagues reported that 11 eyes of 11 study patients had a mean follow-up time of 6.5 ± 2.4 months.
The corrected distance and the corrected near VAs improved significantly. The CDVA improved from 17.00 ± 9.74 to 26.00 ± 8.53) letters (P = 0.008 and the CNVA improved from 12.27 ± 4.36 to 8 ± 2.61 Jaeger levels; P = 0.004). The mean ECL was 4.8% ± 5.5% at 3 months. No complications developed intraoperatively.
According to the investigators, postoperative complications developed that included iris incarceration (9.1%), pigment deposition on the device (9.1%) and transient corneal oedema (27.3%).
Ten of the eleven patients (90.9%) reported blurred or hazy vision within 3 months postoperatively, which resulted in explantation in three patients (27.3%).
Adamo and colleagues concluded, “Although SING IMT implantation is associated with promising objective results, unexplained blurred or hazy vision represents common postoperative complaints, which may lead to patient dissatisfaction. Further studies including patient-reported outcomes are warranted to evaluate the effect of the intervention on patients’ visual function and quality of life.”
