Lynda Charters Enoch started her early “eye life” at the Schepens Eye Research Institute, Boston, which ultimately culminated in her current position as an Editor of Ophthalmology Times.
In the study, investigators conducted a cross-sectional study with the goal of evaluating a correlation between the number of peer-reviewed publications published before a residency and the subsequent peer-reviewed publications or career choices of doctors who graduated from an ophthalmology residency program.
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Investigators concluded that both formulations of AR-1105 were well-tolerated and provided clinically meaningful and sustained visual improvements in vision and decreased retinal thickening despite that some patients had difficult-to-treat BRVO or CRVO with longstanding edema.
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Heavy silicone oil proves effective, safe for persistent full-thickness macular holes
December 31st 2022The use of heavy silicone oil tamponade in secondary surgery for persistent full-thickness macular holes is a safe and efficient surgical method. Best-corrected visual acuity and minimum linear diameter before surgery may be indicators for anatomical success.
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Gene therapy offers improved retinal sensitivity, visual function, and mobility
December 11th 2022In a multicenter phase 1/2 safety study conducted in the US and UK, researchers conducted a dose-escalation trial of AAV5-RPGR that included low, intermediate, and high doses of the gene therapy administered to 3, 4, and 3 adults, respectively.
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COPD & the eye: Ocular microstructures affected by chronic disease
November 7th 2022In both patients and controls, investigators measured retinal nerve fiber layer thickness, foveal avascular zone area, and vessel density in the superficial capillary plexus, deep capillary plexus, and radial peripapillary capillary plexus.
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Timing is everything with early treatment of AMD
November 3rd 2022In a real-world setting, eyes with AMD with a relatively good initial best-corrected visual acuity and no fibrovascular pigment epithelial detachment sustained or improved BCVA after anti-VEGF therapy within 3 years of follow-up.
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Sailing study and extension study: Superiority of conbercept over laser in DME
November 1st 2022The Sailing study was a 12-month, 18-center, randomized, double-masked, double-sham, parallel-controlled, phase 3 trial that was conducted in China and included eyes with center-involved DME that were randomly assigned to undergo either laser photocoagulation followed by as-needed sham intravitreal injections or sham laser photocoagulation followed by as-needed 0.5 mg intravitreal injections of conbercept.
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Cataract surgery in RP patients yield marked improvements in BCVA
October 29th 2022In this retrospective, non-comparative clinical study, the investigators evaluated the preoperative, intraoperative, and postoperative data of the 225 study patients (295 eyes; mean patient age, 56.1 years) collected from several European centers.
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Association between BMI and retinal structural changes investigated
October 19th 2022In this cross-sectional study, investigators used OCTA to identify possible associations between body mass index and the waist-to-hip ratio with macular vessel density and foveal avascular zone in healthy Chinese adults.
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Ranibizumab recall: Genentech recalls ocular implant in the US
October 18th 2022The company noted that testing of a commercial supply of the implants, which included exposing them to multiple punctures with a needle, found they did not meet their standards. The company has notified the FDA, and is working with the agency on the recall process.
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Retinal nerve fiber layer thinning associated with the degree of smoking in patients with POAG
October 17th 2022Investigators conducted a longitudinal study of the relationship between smoking and smoking intensity and the rate with which the retinal nerve fiber layer becomes thinner in patients with primary open-angle glaucoma.
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No significant association found between anti-VEGF therapy for ROP and pulmonary hypertension
October 15th 2022Anti-VEGF therapy for ROP has potential ocular and systemic advantages compared with laser but also noted that the systemic risks of anti-VEGF therapy in these infants need to be quantified.
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